Semaglutide 10mg Lyophilized Vial

Semaglutide 10mg Lyophilized Vial is a high-fill GLP-1 receptor agonist peptide raw material produced by our factory, sealed in vials in lyophilized form with 10mg net content per vial. Semaglutide is a structurally modified long-acting GLP-1 analog whose molecule has three key modifications based on the natural GLP-1 (7-37) sequence: position 8 alanine replaced with Aib to enhance anti-enzymatic ability, position 26 lysine side chain coupled to C18 fatty acid (octadecanedioic acid mono-tert-butyl ester) for albumin binding and extended half-life, position 34 lysine mutated to arginine to avoid fatty acid side chain misconnection. Our finished product is a white loose lyophilized powder.

 

Our factory has accumulated rich process experience in large-scale production of Semaglutide 10mg Lyophilized Vial. The 31-amino-acid sequence contains multiple difficult coupling sites. We elevated crude product quality by alternately using HBTU/HOBt and DIC/HOBt double-coupling systems, extending reaction times and increasing coupling cycles at difficult sites, reducing subsequent purification pressure. In purification, we use preparative reverse-phase HPLC with TFA-acetonitrile gradient for efficient target-impurity separation. Purified peptide solution is desalted, sterile-filtered, quantitatively filled, then vacuum freeze-dried. Every batch undergoes strict quality testing ensuring molecular weight and microbial indicators meet standards, providing stable reliable peptide raw material supply to global customers.

We have dedicated after-sales specialists following up on logistics and answering technical questions throughout. Pre-sales: professional foreign trade sales provide product parameters, COA samples, customized quotes, and technical consultation. In-sales: all order details verified, production scheduled, real photos sent at each stage (charging, synthesis, purification, packaging), tracking number provided after shipment with continuous updates. After-sales: goods receipt followed up, technical inquiries responded within 24 hours. If goods arrive damaged, customers provide clear photos/videos of outer packaging and product damage within 48 hours, and we will quickly verify and arrange replacement or partial refund based on actual situation.

We provide flexible payment terms. Standard spot products require 100% full payment with immediate production and shipment upon confirmation. Customized products require 50% advance to start production, with the remaining 50% settled before shipment. For long-term returning customers, more flexible arrangements can be negotiated. Large orders enjoy tiered discounts - larger volume means better unit price, specific discounts negotiable at inquiry. Settlement in USD and RMB supported. Trade terms default to DDP (Delivered Duty Paid), where we bear all transportation costs, insurance, and customs clearance from factory to customer's designated warehouse, greatly simplifying cross-border procurement.

Our factory has over 20 years of technical accumulation in peptide synthesis and production, covering a total area of 25,000 square meters, with a core production area of a Class 100,000 GMP cleanroom (12,000 sqm), equipped with independent R&D laboratories, quality control testing centers, and raw material storage areas. The factory employs 118 people, including 25 R&D technicians, 35 QC inspectors, and 58 production workers. We have established an integrated fully automated solid-phase peptide synthesis production line using a closed production mode with automatic temperature and pH control, covering the entire process from amino acid charging, solid-phase synthesis, crude cleavage, chromatographic purification, desalting/concentration, sterile filtration, vacuum lyophilization to aseptic filling. The production line supports laboratory-scale R&D, pilot-scale amplification, and large-scale industrial mass production, with a stable monthly capacity of over 30,000 vials, and multiple GMP lines can be scheduled in parallel to ensure on-time delivery of large orders.