Acetyl Hexapeptide-8 Powder 1g

Acetyl Hexapeptide-8 Powder 1g is a cosmetic-grade hexapeptide raw material produced by our factory, with sequence acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂), supplied as white powder. Acetyl Hexapeptide-8, also known as Argireline, is a neurotransmitter-inhibiting peptide whose molecular structure mimics the N-terminal hexapeptide sequence of SNAP-25 protein, capable of competitively binding to vesicle fusion protein complexes, thereby inhibiting calcium-dependent release of acetylcholine at neuromuscular junctions. Our Acetyl Hexapeptide-8 Powder 1g is prepared by solid-phase peptide synthesis, with N-terminal acetylation and C-terminal amidation achieved in one step via dedicated resins and reagents, purified then dried into powder, finished as white to off-white loose powder with good water solubility.

 

In production of Acetyl Hexapeptide-8 Powder 1g, we pay special attention to synthesis quality at arginine and methionine sites. The consecutive two arginines (Arg-Arg) at the C-terminus are prone to coupling reagent deactivation due to the strong basicity of guanidino groups during solid-phase synthesis. We ensured coupling efficiency in this region by using stronger condensation reagent systems, extending coupling reaction time, and implementing double-coupling strategy at difficult sites. Methionine residues are prone to oxidation to sulfoxide during purification and storage; we effectively controlled methionine oxidation impurity generation by adding trace antioxidants to purification solvents, using low-temperature drying, and nitrogen-flushed packaging. Each batch undergoes appearance, HPLC, mass spectrometry, pH, and microbial limit testing with COA report. This product is a widely used active peptide raw material in anti-wrinkle and anti-aging skincare, suitable for serums, creams, eye creams and other formulation systems.

We provide flexible Acetyl Hexapeptide-8 customization services. For specs, beyond standard 1g powder, we can offer 5g, 10g, 50g, 100g and other packaging specs; for packaging, we support customization of vial types, label styles, and outer carton labeling, with packaging designable per customer brand. For product forms requiring specific concentration pre-solutions or different pH adjustments, our R&D team can provide formulation suggestions and process development services. Custom project cycle is generally 15-20 days, no MOQ requirement, supporting flexible switching between small-batch trial and large-batch stable supply; customers can mix different specs or packaging forms in one order.

We have dedicated after-sales specialists following up on logistics and answering technical questions throughout. Pre-sales: professional foreign trade sales provide product parameters, COA samples, customized quotes, and technical consultation. In-sales: all order details verified, production scheduled, real photos sent at each stage, tracking number provided after shipment with continuous updates. After-sales: goods receipt followed up, technical inquiries responded within 24 hours. If goods arrive damaged, customers provide clear photos/videos within 48 hours, and we will quickly verify and arrange replacement or partial refund.

We provide flexible payment terms. Standard spot products require 100% full payment with immediate production and shipment upon confirmation. Customized products require 50% advance to start production, with the remaining 50% settled before shipment. For long-term returning customers, more flexible arrangements can be negotiated. Large orders enjoy tiered discounts - larger volume means better unit price, specific discounts negotiable at inquiry. Settlement in USD and RMB supported. Trade terms default to DDP (Delivered Duty Paid), where we bear all transportation costs, insurance, and customs clearance from factory to customer's designated warehouse, greatly simplifying cross-border procurement.